Jurnale medicale
2014
American Journal of Hematology
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Aesthetic Surgery Journal Allergy Am J Psychiatry current issue American Journal of Clinical Nutrition current issue American Journal of Geriatric Psych - Featured Articles - Featured Articles American Journal of Hematology American Journal of Obstetrics & Gynecology American Journal of Ophthalmology American Journal of Physical Medicine & Rehabilitation - Current Issue Anaesthesia & Intensive Care Medicine Anesthesiology - Current Issue ANZ Journal of Surgery Archives of Physical Medicine and Rehabilitation Arteriosclerosis, Thrombosis, and Vascular Biology current issue
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Diabetes Care Journal current issue Diabetes Journal current issue Diabetes Spectrum Journal current issue
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International Journal of Dental Hygiene International Journal of Emergency Medicine International Journal of Nephrology and Renovascular Disease International Journal of Paediatric Dentistry International Journal of Rheumatic Diseases
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Radiographics current issue Radiology current issue Rheumatology - current issue
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The American Journal of Human Genetics The American Journal of Surgery The British Journal of Diabetes & Vascular Disease current issue The Clinical Respiratory Journal The European Journal of Orthodontics - current issue The Journal of Bone & Joint Surgery current issue The Journal of Clinical Endocrinology & Metabolism Current Issue The Journal of Pathology The Journal of Urology The Lancet The Lancet Infectious Diseases The Lancet Neurology The Lancet Oncology The Oncologist current issue
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Jurnale medicale American Journal of Hematology, 2014

30 Decembrie 2014 05:44

Abstract

International guidelines on immune thrombocytopenia (ITP) management recommend vaccination against Streptococcus pneumoniae (S.p.), Haemophilus influenza b (Hib) and Neisseiria meningitidis (N.m.) before splenectomy. French guidelines also recommend these vaccinations before rituximab. The

mai mult
American Journal of Hematology
24 Decembrie 2014 10:41

Abstract

Prior study of the combination of clofarabine and high dose cytarabine with granulocyte colony-stimulating factor (G-CSF) priming (GCLAC) in relapsed or refractory acute myeloid leukemia resulted in a 46% rate of complete remission despite unfavorable risk cytogenetics. A multivariate analy

mai mult
American Journal of Hematology
24 Decembrie 2014 10:22

Abstract

Fifty-one polycythemia vera (PV) patients were enrolled in the phase I/II clinical study PEGINVERA to receive a new formulation of pegylated interferon alpha (peg-proline-IFN?-2b, AOP2014/P1101). Peg-proline-IFN?-2b treatment led to high response rates on both hematologic and molecular le

mai mult
American Journal of Hematology
24 Decembrie 2014 10:15
24 Decembrie 2014 10:02
23 Decembrie 2014 05:12
23 Decembrie 2014 05:12
23 Decembrie 2014 05:12

Disease overview: Approximately one-fourth of cutaneous lymphomas are B-cell derived and are generally classified into three distinct subgroups: primary cutaneous follicle center lymphoma (PCFCL), primary cutaneous marginal zone lymphoma (PCMZL), and primary cutaneous diffuse large B-cell lymphoma,

mai mult
American Journal of Hematology
22 Decembrie 2014 08:50

Abstract

To investigate the factors that affect molecular responses on dasatinib treatment in patients with chronic-phase chronic myeloid leukemia (CML-CP), we performed a clinical trial named the ??D-First study'. Fifty-two patients with newly diagnosed CML-CP were enrolled in this study and recei

mai mult
American Journal of Hematology
22 Decembrie 2014 08:22

Abstract

We investigated the combination of midostaurin and azacitidine (AZA) in patients with AML and high risk MDS. Patients received AZA 75mg/m2 on days 1-7 and midostaurin 25mg bid (in cohort 1 of phase I) or 50mg bid (in cohort 2 of Phase I and in Phase II) orally on day 8-21 during the first c

mai mult
American Journal of Hematology
19 Decembrie 2014 05:23
16 Decembrie 2014 20:48

Abstract

Genetic ablation of the ferrireductase STEAP3, also known as TSAP6, leads to severe microcytic and hypochromic red cells with moderate anemia in the mouse. However, the mechanism leading to anemia is poorly understood. Previous results indicate that TSAP6/Steap3 is a regulator of exosome se

mai mult
American Journal of Hematology
10 Decembrie 2014 16:17

Abstract

High dose chemotherapy with autologous stem cell transplantation (ASCT) has been shown effective in the control of relapsed/refractory follicular lymphoma. We evaluate the long-term outcome of patients with relapsed or refractory follicular lymphoma treated with ASCT with in vivo purged pro

mai mult
American Journal of Hematology
9 Decembrie 2014 07:58
9 Decembrie 2014 07:56
9 Decembrie 2014 07:50

Abstract

Blood eosinophilia (??0.5x109/l) may be an early sign of hematological malignancy. We investigated associations between levels of blood eosinophils and risks of hematological malignancies and mortality in order to provide clinically derived cut-offs for referral to specialist hematology ca

mai mult
American Journal of Hematology
8 Decembrie 2014 08:26
8 Decembrie 2014 08:24
2 Decembrie 2014 16:04

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome characterized by the activation of the mononuclear phagocytic system. The diagnosis of HLH in adults is challenging not only because the majority of the reported data are from pediatric patients, but also because HLH occur

mai mult
American Journal of Hematology
2 Decembrie 2014 15:57

Summary

A minority of super-utilizing adults with sickle cell disease (SCD) account for a disproportionate number of emergency department (ED) and hospital admissions. We performed a retrospective cohort study comparing the rate of admission before and after the opening of a clinic for adults with S

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American Journal of Hematology
26 Noiembrie 2014 16:35

Abstract

We report our experience on bendamustine and rituximab (BR) combination in 26 patients with chronic lymphocytic leukemia (CLL) complicated by autoimmune hemolytic anemia (AIHA). At the time of BR initiation, 88% of the patients had already been treated for AIHA and CLL was progressive regar

mai mult
American Journal of Hematology
26 Noiembrie 2014 16:26

Abstract

IgM monoclonal gammopathies, such as Waldenstr??m macroglobulinemia (WM), monoclonal gammopathy of undetermined significance (IgM-MGUS) or multiple myeloma (IgM-MM) may be identified based on demonstration of IgM monoclonal protein. We investigated of circulating serum microRNA (miRNA) migh

mai mult
American Journal of Hematology
25 Noiembrie 2014 07:40

Abstract

X-linked thrombocytopenia with thalassemia (XLTT) is caused by the mutation 216R>Q in exon 4 of the GATA1 gene. Male hemizygous patients display macrothrombocytopenia, splenomegaly and a ?-thalassemia trait. We describe two XLTT families where three males were initially misdiagnosed as hav

mai mult
American Journal of Hematology
25 Noiembrie 2014 07:38

Abstract

Patients with secondary AML often escape inclusion in clinical trials and thus, population-based studies are crucial for its accurate characterization. In this first large population-based study on secondary AML, we studied AML with an antecedent hematological disease (AHD-AML) or therapy-r

mai mult
American Journal of Hematology
24 Noiembrie 2014 09:16
22 Noiembrie 2014 07:47
22 Noiembrie 2014 07:47
21 Noiembrie 2014 15:33

Abstract

Hepatitis C virus (HCV) infection increases the risk of B-cell non-Hodgkin lymphomas (B-NHL). Antiviral treatment (AT) can induce hematological responses in patients with marginal zone lymphomas (MZL). The ANRS HC-13 Lympho-C study aimed at a better understanding of the impact of AT on HCV

mai mult
American Journal of Hematology
20 Noiembrie 2014 07:31

Abstract

Imatinib was the first BCR-ABL tyrosine kinase inhibitor (TKI) developed for the treatment of patients with chronic myeloid leukemia (CML); subsequently, the introduction of more potent BCR-ABL TKIs has raised expectations regarding the speed and depth of response. This review discusses how

mai mult
American Journal of Hematology
19 Noiembrie 2014 11:12

Disease Overview: Immunoglobulin light chain amyloidosis is a clonal, nonproliferative plasma cell disorder in which fragments of immunoglobulin light chain are deposited in tissues. Clinical features depend on organs involved but can include restrictive cardiomyopathy, nephrotic syndrome, hepatic f

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American Journal of Hematology
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