Jurnale medicale [no title]
This issue provides a clinical overview of sarcoidosis focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits.
Only ACP members and individual subscribers can access the electronic features of In themai mult [no title]
Identifying risk factors for breast cancer specific to women in their 40s could inform screening decisions.
To determine what factors increase risk for breast cancer in women aged 40 to 49 years and the magnitude of risk for each factor.
MEDLINE (January 1996 to
Circulating concentrations of 25-hydroxyvitamin D [25-(OH)D] are used to define vitamin D deficiency. Current clinical 25-(OH)D targets based on associations with intermediate markers of bone metabolism may not reflect optimal levels for other chronic diseases and do not account for know
Timing of initiation of screening for breast cancer is controversial in the United States.
To determine the threshold relative risk (RR) at which the harm–benefit ratio of screening women aged 40 to 49 years equals that of biennial screening for women aged 50 to 74 years.
Despite recent improvements in survival after acute myocardial infarction (AMI), U.S. hospitals vary 2-fold in their 30-day risk-standardized mortality rates (RSMRs). Nevertheless, information is limited on hospital-level factors that may be associated with RSMRs.
Dementia disorders are characterized by clinicopathological criteria. Molecular understandings of these disorders, based on immunohistochemical studies, biochemical investigations, genetic approaches, and animal models, have resulted in advances in diagnosis. Likewise, translational research has allmai mult [no title]
Objective To report the first prenatal dopaminergic replacement therapy in autosomal recessive (AR) guanosine triphosphate cyclohydrolase 1 (GTPCH) deficiency without hyperphenylalaninemia.
Design Case reports, literature review, and video presentation.
Setting University of Lübeck, Lübeck, Germamai mult [no title]
Objectives To evaluate the diagnostic utility and clinical characteristics of painful tonic spasm (PTS) in neuromyelitis optica (NMO).
Design Retrospective study.
Setting Two referral hospitals.
Patients Forty patients who had NMO spectrum disorder with anti–aquaporin 4 autoantibody or met the rmai mult [no title]
Basic research in neuroscience and clinical research on neurological disorders synergistically increase our understanding of the human brain. Traditionally, functional and clinical studies of the human brain were limited to postmortem histology, "natural experiments" (eg, lesions to brain areas causmai mult [no title]
Background Given the slow and variable clinical course of Alzheimer disease, very large and extended clinical trials are needed to identify a beneficial clinical effect of disease-modifying treatments. Therefore, biomarkers are essential to prove that an anti–β-amyloid (Aβ) drug candidate affects bmai mult [no title]
Objective To describe the clinical course of an unusually severe case of minocycline-induced intracranial hypertension.
Design Case study.
Setting Academic medical center.
Patient Twelve-year-old girl with a fulminant course of intracranial hypertension.
Interventions Magnetic resonance imagingmai mult [no title]