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The American Journal of Human Genetics The American Journal of Surgery The British Journal of Diabetes & Vascular Disease current issue The Clinical Respiratory Journal The European Journal of Orthodontics - current issue The Journal of Bone & Joint Surgery current issue The Journal of Clinical Endocrinology & Metabolism Current Issue The Journal of Pathology The Journal of Urology The Lancet The Lancet Infectious Diseases The Lancet Neurology The Lancet Oncology The Oncologist current issue
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Jurnale medicale BMC Gastroenterology - Latest Articles

5 Februarie 2015 12:00
Background: Tofacitinib, a novel, oral Janus kinase inhibitor, demonstrated a dose-dependent efficacy for induction of clinical response and remission in patients with active ulcerative colitis (UC). The objective of the current study was to determine the effect of tofacitinib on patient-reported ou mai mult
BMC Gastroenterology - Latest Articles
5 Februarie 2015 12:00
Background: Colonoscopy offers limited protection against right-sided colon cancer, a significant proportion of which arise from the serrated pathway of carcinogenesis. The aim of this study was to compare cap-assisted colonoscopy and standard high-definition white light colonoscopy regarding serrat mai mult
BMC Gastroenterology - Latest Articles
5 Februarie 2015 12:00
Contributing reviewersThe editors of BMC Gastroenterology would like to thank all our reviewers who have contributed to the journal in Volume 14 (2014). mai mult
BMC Gastroenterology - Latest Articles
5 Februarie 2015 12:00
Background: Cross-sectional imaging techniques as magnetic resonance enterography (MRE) may offer additional information on transmural inflammation, stricturing and fistulising complications in Crohn?s disease (CD). The purpose of our study was to evaluate the diagnostic accuracy of Magnetic Resonan mai mult
BMC Gastroenterology - Latest Articles
5 Februarie 2015
Background: Although poor sleep is common in numerous gastrointestinal diseases, data are scarce on the risk of poor sleep in celiac disease. The objective of this study was to estimate the risk of repeated use of hypnotics among individuals with celiac disease as a proxy measure for poor sleep. Met mai mult
BMC Gastroenterology - Latest Articles
5 Februarie 2015
Background: Intra-tumor heterogeneity is a potential cause for failure of targeted therapy in gastric cancer, but the extent of heterogeneity of established (HER2) or potential (EGFR, CCND1) target genes and prognostic gene alterations (MYC) had not been systematically studied. Methods: To study het mai mult
BMC Gastroenterology - Latest Articles
5 Februarie 2015
Background: Endoscopic biliary stenting (EBS) is one of the most important palliative treatments for biliary tract cancer. However, reflux cholangitis arising from bacterial adherence to the inner wall of the stent must be avoided. We evaluated the use of EBS above the sphincter of Oddi to determine mai mult
BMC Gastroenterology - Latest Articles
5 Februarie 2015
Background: Environmental and genetic factors contribute to variation in irritable bowel syndrome (IBS), anxiety and depression. Comorbidity between these disorders is high. A previous investigation of our population-based twin cohort revealed that low birth weight increased the risk for development mai mult
BMC Gastroenterology - Latest Articles
22 Ianuarie 2015 12:00
Background: MicroRNA-21 (miR-21) is an oncogenic microRNA that regulates the expression of multiple cancer-related target genes. miR-21 has been associated with progression of some types of cancer. Metastasis-associated protein1 expression and loss of E-cadherin expression are correlated with cancer mai mult
BMC Gastroenterology - Latest Articles
22 Ianuarie 2015 12:00
Background: Patients with chronic liver disease frequently suffer from malnutrition, together with a decline in their health-related quality of life.This study was carried out with the aim of evaluating the nutritional status, complications of medical and surgical care, anxiety, health-related quali mai mult
BMC Gastroenterology - Latest Articles
22 Ianuarie 2015 12:00
Background: Celiac disease (CD) is a global health problem and its prevalence is underestimated, especially in Latin American populations. Our aim was to evaluate the clinical features, psychological factors, and health-related quality of life (QoL), before and after diagnosis, in a representative s mai mult
BMC Gastroenterology - Latest Articles
22 Ianuarie 2015 12:00
Background: Esophageal stenosis following endoscopic submucosal dissection (ESD) is a serious adverse event that makes subsequent management more difficult. Methods: This parallel, randomized, controlled, open-label study was designed to examine whether local steroid injection is an effective prophy mai mult
BMC Gastroenterology - Latest Articles
22 Ianuarie 2015 12:00
Background: In this study, we evaluated the technical feasibility of mucosal approximation of large ulcers via an endoscopic suturing system after endoscopic submucosal dissection (ESD), assessed the durability of these sutures, and compared this technique with serosal apposition of full-thickness g mai mult
BMC Gastroenterology - Latest Articles
22 Ianuarie 2015 12:00
Background: The prevalence of obesity has increased at alarming rates, particularly because of the increased consumption of high-fat diets (HFDs). The influence of HFDs on intrinsic innervation and the intestinal wall has not been fully characterized. The aim of this study was to investigate the mor mai mult
BMC Gastroenterology - Latest Articles
31 Decembrie 2014 12:00
Background: Investigations of genetic alterations and correlations with histology or morphology could provide further insights into colorectal carcinogenesis. Nevertheless, such genetic changes were less investigated in adenoma stage and a comprehensive survey of oncogenic mutations in EGFR signalin mai mult
BMC Gastroenterology - Latest Articles
31 Decembrie 2014 12:00
Background: Precise diagnostics of inflammatory bowel disease (IBD) and identification of potentially more aggressive phenotypes of Crohn?s disease (CD) is urgently needed. The aim of our prospective study was to assess the relationship between serum anti-OmpC IgA (Outer membrane protein C), anti-GP mai mult
BMC Gastroenterology - Latest Articles
31 Decembrie 2014 12:00
Background: Activated hepatic stellate cells are the main source of excessive collagen deposition in liver fibrosis. Here we report the inhibitory effects of the combinational treatment of two natural products, astragalus polysaccharide (APS) and ?-elemene (ELE) on the activation of human liver hepa mai mult
BMC Gastroenterology - Latest Articles
24 Decembrie 2014
Background: Wireless pH-monitoring is an accurate method for diagnosing adults with gastroesophageal reflux disease (GERD). The aim of this study was to evaluate the use of the Bravo capsule on children investigated for GERD in terms of safety, tolerability and feasibility before and after administr mai mult
BMC Gastroenterology - Latest Articles
24 Decembrie 2014
Background: Type 2 diabetes mellitus (T2DM) is a progressive disease resulting from increasing insulin resistance and reduced pancreatic ?-cell insulin secretion. Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibits insulin signalling and may contribute to the pathogenesis of T2DM. Ot mai mult
BMC Gastroenterology - Latest Articles
24 Decembrie 2014
Background: Helicobacter pylori chronic infection is associated with chronic gastritis, peptic ulcer, and gastric cancer. Cytotoxin-associated gene A (cagA)-positive H. pylori strains increase the risk of gastric pathology. The carcinogenic potential of CagA is linked to its polymorphic EPIYA motif mai mult
BMC Gastroenterology - Latest Articles
18 Decembrie 2014 12:00
Background: We aimed at assessing the factors that can influence results of the dissemination of an already validated, new generation commercial Point-of-Care Test (POCT) for detecting celiac disease (CD), in the Mediterranean area, when used in settings where it was designed to be administered, esp mai mult
BMC Gastroenterology - Latest Articles
18 Decembrie 2014 12:00
Background: Functional gastrointestinal disorders (FGID) are defined by a combination of chronic or recurrent gastrointestinal symptoms. Prevalence rates of FGID are high. Symptoms are associated with distress, and sufferers show high stress levels. However, the current diagnostic criteria do not co mai mult
BMC Gastroenterology - Latest Articles
19 Decembrie 2014 12:00
Background and aimHBV and HCV reactivation have been widely reported in patients undergoing immunosuppressive therapy (IT); however, few data are available on the risk of reactivation in patients with psoriasis receiving IT. The aim of our study was to assess the prevalence of HBV and HCV infection mai mult
BMC Gastroenterology - Latest Articles
19 Decembrie 2014 12:00
Background: Non-invasive models and methods to substitute liver biopsy in chronic hepatitis B (CHB) patients were investigated but their roles as predictors of significant liver histology for diagnosis of HBeAg-negative CHB patients who had indication for liver biopsy according to The American Assoc mai mult
BMC Gastroenterology - Latest Articles
19 Decembrie 2014 12:00
Background: Non-adherence to aminosalicylates is observed among 30% to 45% of patients with ulcerative colitis and increases the risk of relapse. The Health Belief Model is a theoretical model that could offer a broader perspective to improve patients? self-medication adherence. This study aimed to mai mult
BMC Gastroenterology - Latest Articles
21 Decembrie 2014 12:00
Background: Faecal immunochemical tests (FITs) are commonly used in colorectal cancer (CRC) screening. Diagnostic accuracy of FIT differs between males and females. This so far unexplained difference could result in a dissimilarity in screening outcome between both sexes. The aim of this study is to mai mult
BMC Gastroenterology - Latest Articles
16 Decembrie 2014 12:00
Background: Early life exposures may modify risk of inflammatory bowel diseases (IBD; Crohn?s disease (CD), ulcerative colitis (UC)). However, the relationship between early life exposures and natural history of IBD has not been previously examined. Methods: This single center study included patients mai mult
BMC Gastroenterology - Latest Articles
16 Decembrie 2014 12:00
Background: Visceral obesity is often accompanied by non-alcoholic fatty liver disease (NAFLD). Activation of NACHT, LRR and PYD domains-containing proteins (NALPs) may contribute to the release of pro-inflammatory cytokines by adipose and the obesity-associated progression of NAFLD to non-alcoholic mai mult
BMC Gastroenterology - Latest Articles
17 Decembrie 2014
Background: Obesity and related metabolic abnormalities, including excess oxidative stress and chronic inflammation, are associated with colorectal carcinogenesis. Astaxanthin, a xanthophyll carotenoid found in aquatic animals, is known to possess antioxidant, anti-inflammatory, and antineoplastic p mai mult
BMC Gastroenterology - Latest Articles
13 Decembrie 2014 12:00
Background: Whether non-alcoholic fatty liver disease (NAFLD) is a risk factor for gallstones remains uncertain. Few longitudinal or cohort studies have been used to identify this relationship. The aim of this study was to confirm the association between NAFLD and gallstones in a longitudinal cohort mai mult
BMC Gastroenterology - Latest Articles
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