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Jurnale medicale
Chirurgie cardiovasculara

Jurnale medicale Chirurgie cardiovasculara

6 Februarie 2015 21:05
6 Februarie 2015 21:05
6 Februarie 2015 21:05
Background—

The contemporary practice patterns and role of catheter-directed thrombolysis (CDT) in the treatment of inferior vena cava thrombosis is unknown.

Methods and Results—

The Nationwide Inpatient Sample database was used to identify patients with a principal discharge diagnosis of inferior

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Circulation: Cardiovascular Interventions current issue
5 Februarie 2015 21:00
Background—

Eptifibatide, a small-molecule glycoprotein IIb/IIIa inhibitor, is conventionally administered as a bolus plus infusion. A growing number of clinicians are using a strategy of catheterization laboratory–only eptifibatide (an off-label use) as procedural pharmacotherapy for patients under

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Circulation: Cardiovascular Interventions current issue
5 Februarie 2015 21:00
Background—

Up to 1 in 6 patients undergoing transcatheter aortic valve implantation (TAVI) present with low-ejection fraction, low-gradient (LEF-LG) severe aortic stenosis and concomitant relevant mitral regurgitation (MR) is present in 30% to 55% of these patients. The effect of MR on clinical out

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Circulation: Cardiovascular Interventions current issue
5 Februarie 2015 21:00
5 Februarie 2015 21:00
5 Februarie 2015 21:00
4 Februarie 2015 21:00
Background—

Percutaneous pulmonary valve implantation (PPVI) is a safe, less invasive alternative to surgical valve replacement for the congenital heart disease patient with right ventricular (RV) outflow tract dysfunction. The aim of this study was to determine whether reverse RV remodeling after P

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Circulation: Cardiovascular Interventions current issue
4 Februarie 2015 21:00
Background—

There is a conflicting evidence on safety and efficacy of transcatheter aortic valve implantation in patients with preoperative chronic kidney disease (CKD). Therefore, we conducted a meta-analysis on the impact of CKD on outcomes after transcatheter aortic valve implantation.

Methods a mai mult
Circulation: Cardiovascular Interventions current issue
4 Februarie 2015 21:00
4 Februarie 2015 21:00
Background—

The pathology of radiofrequency-derived sympathetic renal denervation has not been studied over time and may provide important understanding of the mechanisms resulting in sustained blood pressure reduction. The purpose of this study was to investigate chronological changes after radiofr

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Circulation: Cardiovascular Interventions current issue
29 Ianuarie 2015 21:00
Background—

Biodegradable polymers for release of antiproliferative drugs from drug-eluting stents aim to improve vascular healing. We assessed noninferiority of a novel ultrathin strut drug-eluting stent releasing sirolimus from a biodegradable polymer (Orsiro, O-SES) compared with the durable poly

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Circulation: Cardiovascular Interventions current issue
29 Ianuarie 2015 21:00
26 Ianuarie 2015 21:01
Background and Purpose—

Multiple studies have shown that negative computed tomographic angiograms (CTAs) are reliable in excluding aneurysms in patients with isolated perimesencephalic subarachnoid hemorrhage (pSAH). We evaluate the use of digital subtraction angiography versus CTA for initial diagn

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

We examined blood pressure 1 year after stroke discharge and its association with treatment intensification.

Methods—

We examined the systolic blood pressure (SBP) stratified by discharge SBP (≤140, 141–160, or >160 mm Hg) among a national cohort of Veterans discharged after

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

The Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke-Enhanced Regimen (CLEAR-ER) trial demonstrated safety of recombinant tissue-type plasminogen activator (r-tPA) plus eptifibatide in acute ischemic stroke (AIS). CLEAR-ER randomized AIS pa

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Stroke current issue
26 Ianuarie 2015 21:01
26 Ianuarie 2015 21:01
Background and Purpose—

Fibroblast growth factor 23 (FGF23) is a hormone that regulates phosphorus and vitamin D metabolism. Elevated FGF23 concentrations are associated with excess risk of cardiovascular disease. Associations of FGF23 with stroke outcomes are less clear.

Methods—

Using a case–coho

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

We tested the hypothesis that observationally and genetically elevated YKL-40 is associated with elevated lipids and lipoproteins and with increased risk of ischemic vascular disease.

Methods—

We conducted cohort and Mendelian randomization studies in 96 110 individuals from

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

A better understanding of the stroke risk factors in children with congenital heart disease (CHD) could inform stroke prevention strategies. We analyzed pediatric stroke associated with CHD in a large community-based case–control study.

Methods—

From 2.5 million children (ag

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

White matter hyperintensities (WMH) of presumed vascular origin increase the risk of stroke and dementia. Despite strong WMH heritability, few gene associations have been identified. Relevant experimental models may be informative.

Methods—

We tested the associations between

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

Epidemiological studies suggest that white matter hyperintensities (WMH) are extremely heritable, but the underlying genetic variants are largely unknown. Pathophysiological heterogeneity is known to reduce the power of genome-wide association studies (GWAS). Hypertensive and

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

The mechanisms underlying frontal lobe dysfunction in moyamoya disease (MMD) are unknown. We aimed to determine whether chronic ischemia induces subtle microstructural brain changes in adult MMD and evaluated the association of changes with neuropsychological performance.

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

The characteristics of intracerebral hemorrhage (ICH) may vary by ICH location because of differences in the distribution of underlying cerebral small vessel diseases. Therefore, we investigated the incidence, characteristics, and outcome of lobar and nonlobar ICH.

Methods— mai mult
Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

Prophylactic anticoagulation for deep venous thrombosis prevention after intracerebral hemorrhage (ICH) is safe. Current guidelines recommend prophylactic anticoagulation after cessation of hematoma growth. We aimed to evaluate nationwide trends in deep venous thrombosis prop

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

We developed and validated a simple algorithm to predict the risk of hematoma growth in acute spontaneous intracerebral hemorrhage (ICH) to better inform clinicians and researchers in their efforts to improve outcomes for patients.

Methods—

We analyzed data from the computed

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

Diffusion MRI is a promising, clinically feasible imaging technique commonly used to describe white matter changes after stroke. We investigated the sensitivity of diffusion MRI to detect microstructural alterations in gray matter after sensorimotor cortex stroke in adult mal

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

Experimental evidence has indicated the benefits of simvastatin for the treatment of subarachnoid hemorrhage. Two randomized placebo-controlled pilot trials that used the highest clinically approved dose of simvastatin (80 mg daily) gave positive results despite the fact that

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Stroke current issue
26 Ianuarie 2015 21:01
Background and Purpose—

Norrin and its receptor Frizzled-4 have important roles in the blood–brain barrier development. This study is to investigate a potential role and mechanism of Norrin/Frizzled-4 on protecting blood–brain barrier integrity after subarachnoid hemorrhage (SAH).

Methods—

One hund

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Stroke current issue
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