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Jurnale medicale
Critical Care - Latest Articles
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Jurnale medicale Critical Care - Latest Articles

6 Februarie 2015
IntroductionUltrasound of the lung and quantification of B-Lines was recently introduced as a novel tool to detect overhydration. In the present study we aimed to evaluate a four region protocol of lung ultrasound to determine the pulmonary fluid status in ventilated patients in the intensive care u mai mult
Critical Care - Latest Articles
5 Februarie 2015
IntroductionThere is need for continuous glucose monitoring in critically ill patients. The objective of this trial was to determine the point accuracy and reliability of a device designed for continuous monitoring of interstitial glucose levels in intensive care unit patients. Methods: We evaluated mai mult
Critical Care - Latest Articles
28 Ianuarie 2015 12:00
28 Ianuarie 2015 12:00
Endothelial cells line the inner portion of the heart, blood vessels, and lymphatic vessels; a basal membrane of extracellular matrix lines the extraluminal side of endothelial cells. The apical side of endothelial cells is the site for the glycocalyx, which is a complex network of macromolecules, i mai mult
Critical Care - Latest Articles
29 Ianuarie 2015 12:00
The results of recent large-scale clinical trials have led us to review our understanding of the metabolic response to stress and the most appropriate means of managing nutrition in critically ill patients. This review presents an update in this field, identifying and discussing a number of areas fo mai mult
Critical Care - Latest Articles
30 Ianuarie 2015
30 Ianuarie 2015
IntroductionThe aim of this study was to explore the impact of augmented creatinine clearance, and differing minimum inhibitory concentrations (MIC), on piperacillin pharmacokinetic/pharmacodynamic (PK/PD) target attainment (time above MIC - fT>MIC), in critically ill septic patients receiving inter mai mult
Critical Care - Latest Articles
2 Februarie 2015
IntroductionThe primary objective of this study was to determine the efficiency of hydrogen peroxide (H2O2) techniques in disinfection of ICU rooms contaminated with multidrug-resistant organisms (MDRO) after patient discharge. Secondary objectives included comparison of the efficiency of a vaporiza mai mult
Critical Care - Latest Articles
2 Februarie 2015
3 Februarie 2015
IntroductionIntravenous (IV) voriconazole is not recommended in patients with creatinine clearance <50?ml/min to avoid potentially toxic accumulation of sulfobutylether-?-cyclodextrin (SBECD). The purpose of this study was to evaluate the pharmacokinetics of SBECD, voriconazole, and voriconazole N-o mai mult
Critical Care - Latest Articles
4 Februarie 2015
IntroductionThe objective of the study was to describe the pharmacokinetics (PK) of fluconazole, anidulafungin and caspofungin in critically ill patients and compare to previously published data. We also sought to determine whether contemporary fluconazole doses achieved PK/pharmacodynamic (PD; PK/PD mai mult
Critical Care - Latest Articles
29 Ianuarie 2015
IntroductionAcute kidney injury (AKI) is a frequent complication after cardiac surgery with cardiopulmonary bypass in infants. Renal near-infrared spectroscopy (NIRS) evaluates regional oximetry in a non-invasive continuous real-time fashion, and reflects tissue perfusion. This study aimed to evalua mai mult
Critical Care - Latest Articles
28 Ianuarie 2015
16 Ianuarie 2015
IntroductionIn critically ill patients, re-intubation is common and may be a high-risk procedure. Anticipating a difficult airway and identifying high-risk patients can allow time for life-saving preparation. Unfortunately, prospective studies have not compared the difficulty or complication rates a mai mult
Critical Care - Latest Articles
16 Ianuarie 2015
19 Ianuarie 2015
IntroductionThe neutrophil-to-lymphocyte ratio (NLR) is a biological marker that has been shown to be associated with outcomes in patients with a number of different malignancies. The objective of this study was to assess the relationship between NLR and mortality in a population of adult critically mai mult
Critical Care - Latest Articles
19 Ianuarie 2015
IntroductionGradual reduction of the dosage of norepinephrine (NE) in patients with septic shock is usually left to the physician?s discretion. No haemodynamic indicator predictive of the possibility of decreasing the NE dosage is currently available at the bedside. The respiratory pulse pressure va mai mult
Critical Care - Latest Articles
20 Ianuarie 2015
IntroductionThis study aimed to evaluate whether fasting plasma citrulline concentration predicts subsequent glucose absorption in critically ill patients. Methods: In a prospective observational study involving 15 healthy and 20 critically ill subjects, fasting plasma citrulline concentrations were mai mult
Critical Care - Latest Articles
20 Ianuarie 2015
IntroductionVenous catheterisation in paediatric patients can be technically challenging. We examined factors affecting catheterisation of invisible and impalpable peripheral veins in children and evaluated the best site for ultrasound-guided catheterisation. Methods: Systolic pressure, age, sex, an mai mult
Critical Care - Latest Articles
22 Ianuarie 2015
IntroductionPatients with acute respiratory failure requiring respiratory support with invasive mechanical ventilation while awaiting lung transplantation are at a high risk of death. Extracorporeal membrane oxygenation (ECMO) has been proposed as an alternative bridging strategy to mechanical venti mai mult
Critical Care - Latest Articles
23 Ianuarie 2015
IntroductionInsulin is used to treat hyperglycaemia in critically ill patients but can cause hypoglycaemia, which is associated with poorer outcomes. In health glucose-dependent insulinotropic polypeptide (GIP) is a potent glucose-lowering peptide that does not cause hypoglycaemia. The objectives of mai mult
Critical Care - Latest Articles
26 Ianuarie 2015
IntroductionThe aim of this study was to assess the effect of low-dose corticosteroid therapy in reducing shock duration after severe burn. Methods: A placebo-controlled, double-blind, randomized clinical trial (RCT) was performed on two parallel groups in the burn intensive care unit (ICU). Patient mai mult
Critical Care - Latest Articles
27 Ianuarie 2015
IntroductionThe value of gastric intramucosal pH (pHi) can be calculated from the tonometrically measured partial pressure of carbon dioxide ( P C mai mult
Critical Care - Latest Articles
31 Decembrie 2014
IntroductionTo derive literature-based summary estimates of readmission to ICU and hospital mortality for patients discharged alive from ICU. Methods: We searched MEDLINE, EMBASE, CINAHL and the Cochrane Central Register of Controlled Trials from inception to March 2013, as well as reference lists o mai mult
Critical Care - Latest Articles
22 Decembrie 2014
29 Decembrie 2014 12:28
The meta-analysis of early goal-directed therapy (EGDT) by Gu and colleagues in the previous issue of Critical Care adds to the ongoing controversy about the value of EGDT for resuscitating patients with severe sepsis and septic shock. The results of the ProCESS (protocolized care for early septic s mai mult
Critical Care - Latest Articles
27 Decembrie 2014 05:09
Fluid bolus therapy (FBT) is a standard of care in the management of the septic, hypotensive, tachycardic and/or oliguric patient. However, contemporary evidence for FBT improving patient-centred outcomes is scant. Moreover, its physiological effects in contemporary ICU environments and populations mai mult
Critical Care - Latest Articles
26 Decembrie 2014 12:06
The study by Hincker and colleagues indicated that the perioperative use of rotational thrombelastometry (ROTEM??) could predict thromboembolic events in 90% of the cases in non-cardiac surgery. Viscoelastic tests (VETs) - ROTEM?? and thrombelastography (TEG??) - are used mainly to predict bleedi mai mult
Critical Care - Latest Articles
25 Decembrie 2014
IntroductionData on the incidence of a hypercoagulable state in trauma, as measured by thromboelastometry (ROTEM), is limited and the prognostic value of hypercoagulability after trauma on outcome is unclear. We aimed to determine the incidence of hypercoagulability after trauma, and to assess wheth mai mult
Critical Care - Latest Articles
23 Decembrie 2014 12:09
Endothelial glycocalyx degradation induced by fluid overload adds to the concern of a detrimental effect of uncontrolled fluid resuscitation and the risk of unnecessary fluid infusion. As a consequence, the use of new tools for monitoring response to fluids appears promising. From that perspective, mai mult
Critical Care - Latest Articles
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