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Heart current issue
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Jurnale medicale Heart current issue

29 Ianuarie 2015 14:24

Dear Editor,

The learning points that Luther and colleagues have raised from this case are well made.1 Brief limb-jerking is not uncommon during syncope, and such ‘convulsive syncope’ may lead to an incorrect diagnosis of epilepsy and/or unnecessary referral to a neurology service. This misdiagnosis

mai mult
Heart current issue
29 Ianuarie 2015 14:24
Objective

To study the impact of national economic and human development status on patient profiles and outcomes in the setting of acute coronary syndrome (ACS).

Methods

We conducted a retrospective analysis of the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acu

mai mult
Heart current issue
29 Ianuarie 2015 14:24
CLINICAL INTRODUCTION

A 36-year-old woman was referred to our neurological and cardiological services with recurrent blackouts. She was diagnosed at age 6 with nocturnal generalised tonic-clonic seizures, which settled by age 13 with Carbamazepine. During adulthood, her seizures were thought to have

mai mult
Heart current issue
29 Ianuarie 2015 14:24
Objective

To investigate clinical outcomes of coronary intervention using a biolimus-eluting stent (BES) compared with a sirolimus-eluting stent (SES) in patients with acute myocardial infarction (AMI) in the Limus Eluted from A Durable versus ERodable Stent (LEADERS) coating trial at the final 5-ye

mai mult
Heart current issue
29 Ianuarie 2015 14:24

Learning objectives

  • Learn the current definition and classification of pulmonary hypertension.

  • Learn the role of different diagnostic techniques in pulmonary hypertension.

  • Learn about current medical and surgical treatment of pulmonary (arterial) hypertension.

  • Curriculum topic: Primary pulmonary mai mult
    Heart current issue
    29 Ianuarie 2015 14:24
    Objectives

    Acute management of ST elevation myocardial infarction (STEMI) patients on chronic vitamin K antagonist (VKA) therapy is uncertain. This study aims to estimate in-hospital major bleeding risk among STEMI patients on chronic VKA treated with primary percutaneous coronary intervention (PCI)

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24
    Objective

    A predictable relation between genotype and disease expression is needed in order to use genetic testing for clinical decision-making in hypertrophic cardiomyopathy (HCM). The primary aims of this study were to examine the phenotypes associated with sarcomere protein (SP) gene mutations an

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24
    Objective

    To assess the relationship between fine particulate matter (PM2.5) concentration and ischaemic heart disease (IHD) morbidity and mortality.

    Methods

    A time-series study conducted in Beijing from 1 January 2010 to 31 December 2012. Data on 369 469 IHD cases and 53 247 IHD deaths were collec

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24

    Randomized controlled trials increasingly recruit patients globally to facilitate recruitment and to improve validity and applicability. However, patients from countries with different developmental status may differ in terms of clinical profiles, adherence to prescribed therapy and access to healt

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24

    Air pollution is a significant cause of cardiovascular morbidity and mortality worldwide. Although the epidemiologic association between air pollution exposures and exacerbation of cardiovascular disease (CVD) is well established, the mechanisms by which these exposures promote CVD are incompletely

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24

    Learning objectives

  • Correct patient selection for renal denervation is of paramount importance to get the best from the procedure. Readers should be able to identify the ideal candidate after reading the article.

  • Beyond pressure lowering effects, renal denervation demonstrated its efficacy in othe

  • mai mult
    Heart current issue
    29 Ianuarie 2015 14:24
    Introduction

    Implantable cardiac electronic devices (ICEDs) comprise permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy (CRT). Implantation rates in the UK are increasing1 and are set to rise further in the wake of recent guidelines that

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24
    Objectives

    Assess the impact of end-stage renal disease (chronic kidney disease stage 5 (CKD5)) on cardiovascular outcomes in patients with Fabry disease on enzyme replacement therapy.

    Background

    Fabry disease, an X-linked lysosomal storage disease, causes hypertrophic cardiomyopathy and cardiovasc

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24

    A large and growing body of research has provided increasingly compelling evidence that exposure to particulate matter (PM) air pollution contributes to cardiovascular disease (CVD) morbidity and mortality.1 Overall, the evidence suggests that fine, combustion-related particulate pollution, measured

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24
    Objective

    To determine the prevalence, clinical correlates and the effects on outcome of vitamin B12 and folic acid levels in patients with chronic heart failure (HF).

    Methods

    We studied an international pooled cohort comprising 610 patients with chronic HF. The main outcome measure was all-cause m

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24

    Cardiovascular disease (CVD) is the leading cause of global mortality and morbidity, and the vast majority of the disease burden is in low-income countries (LICs) and low-income to middle-income countries (LMICs).1 CVD research, including clinical trials, is among the most productive in biomedical s

    mai mult
    Heart current issue
    29 Ianuarie 2015 14:24
    Outcomes with increased length of dual antiplatelet therapy after PCI

    The optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) is uncertain. Although observational studies have suggested DAPT for longer than a year post-PCI reduces ischemic events, othe

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49

    To the Editor

    We are intrigued by the article by Priest and Ashley.1 The importance of genomics has been clearly identified and the article beautifully describes the role of genetics in cardiovascular medicine but concentrates on inherited arrhythmias, cardiomyopathies and occasional pharmacogenomic

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Objectives

    A policy model is a model that can evaluate the effectiveness and cost-effectiveness of interventions and inform policy decisions. In this study, we introduce a cardiovascular disease (CVD) policy model which can be used to model remaining life expectancy including a measure of socioecono

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Dual Antiplatelet Therapy Beyond 1-year after Percutaneous Coronary Interventions for Stable Coronary Artery Disease Results in Harm

    The benefit of extended dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) is uncertain. The ARTIC-Interruption Trial examined discontinua

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Objective

    T wave inversion (TWI) has been associated with cardiomyopathies. The hypothesis of this study was that TWI has relevant clinical significance in peri-pubertal athletes.

    Methods

    Consecutive male soccer players, aged 8–18 years, undergoing preparticipation screening between January 2008 an

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Objective

    Various cardiovascular prediction models have been developed for patients with type 2 diabetes. Their predictive performance in new patients is mostly not investigated. This study aims to quantify the predictive performance of all cardiovascular prediction models developed specifically for

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Objectives

    Remote ischaemic preconditioning (RIPC), using brief cycles of limb ischaemia/reperfusion, is a non-invasive, low-cost intervention that may reduce perioperative myocardial injury (PMI) in patients undergoing cardiac surgery. We investigated whether RIPC can also improve short-term clinic

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Objective

    Women with severe aortic valve stenosis (AS) have better LV systolic function and more concentric LV geometry than their male counterparts. However, sex differences in cardiovascular (CV) outcome during progression of AS have not been reported from a longitudinal prospective study.

    Method mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Objective

    Higher circulating Angiopoietin-2 (Ang-2) levels predict cardiovascular events and mortality in clinical samples and in the general population. To better understand the underlying mechanisms, we investigated the association of circulating Ang-2 and sTie-2 (the soluble form of the Ang-2 rec

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Clinical Introduction

    A 63-year-old woman with a history of dwarfism presented with recurrent palpitations. She denied chest pain, dyspnoea or syncope. Her cardiac exam was notable for tachycardia at 188 bpm, hypotension (77/38) and no overt signs of heart failure. Cardiac markers were negative and

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49

    Transcatheter aortic valve replacement (TAVR) or transcatheter aortic valve implantation (TAVI) has emerged as an attractive treatment strategy for the treatment of patients with severe symptomatic aortic stenosis (AS), particularly those who are inoperable or at high risk for surgical aortic valve

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49
    Objective

    To examine the association of body mass index (BMI), waist circumference (WC) and waist hip ratio (WHR) with sudden cardiac death (SCD) in community dwelling individuals.

    Methods

    Data from a multicentre, prospective, cohort study of 14 941 men and women (African American, and white), aged

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49

    12-lead ECG plays a central role in the cardiovascular evaluation of athletes and highly active patients. Based on the ability of the ECG to detect underlying structural and electrical cardiac disease, the ECG is the most widely used diagnostic test during pre-participation screening of asymptomatic

    mai mult
    Heart current issue
    15 Ianuarie 2015 03:49

    Learning objectives

  • Cardiac resynchronization therapy (CRT) is an established treatment for heart failure patients. However, there remain subpopulations that were underrepresented in randomised controlled trials and for which the benefits of this therapy is less clear.

  • The present review article s

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    Heart current issue
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