Home Jurnale medicale International Journal of Rheumatic Diseases
Jurnale medicale
International Journal of Rheumatic Diseases
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Jurnale medicale International Journal of Rheumatic Diseases

22 Ianuarie 2015 13:17

Abstract

Chylous polyserositis and autoimmune myelofibrosis occurring concomitantly inn a case of SLE are a rare phenomenon. We here report a case of a 38-year-old woman who was admitted with a history of cough and shortness of breath for 1? months along with fever and abdominal distension for 1 m

mai mult
International Journal of Rheumatic Diseases
22 Ianuarie 2015 13:23

Abstract

Mesenchymal stem cells are a rare subset of stem cells residing in the bone marrow where they closely interact with hematopoietic stem cells and support their growth and differentiation. They can suppress proliferation or functions of many immune cells such as T cells, B cells, natural kill

mai mult
International Journal of Rheumatic Diseases
3 Ianuarie 2015 05:27

Abstract

Aim

The aim of this study was to investigate the incidence of tuberculosis (TB) following anti-tumor necrosis factor (TNF) therapy in an intermediate TB burden area and to compare the risk between drugs and diseases.

Methods

The data were obtained from a nationwide database maintained by the

mai mult
International Journal of Rheumatic Diseases
3 Ianuarie 2015 05:43

Abstract

Aim

To investigate the clinical and pathological characteristics of renal involvement in Behcet's disease (BD).

Methods

A retrospective analysis was carried out in BD patients complicated with renal damage who were hospitalized in Peking Union Medical College Hospital from June 1998 to July 2

mai mult
International Journal of Rheumatic Diseases
3 Ianuarie 2015 05:51

Abstract

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with heterogeneous clinical manifestations, and pathologically characterized by activation of autoreactive T cells and overproduction of autoantibodies by B cells. Although corticosteroids and immunosuppressants are wide

mai mult
International Journal of Rheumatic Diseases
31 Decembrie 2014 04:48

Abstract

Aim

Original studies have employed various genetic models in association analysis between ABCG2 Q141K (rs2231142) with gout risk and different or conflicting results, especially regarding the role of gender in this association. In addition, it is not clear whether the association varies by e

mai mult
International Journal of Rheumatic Diseases
31 Decembrie 2014 04:51

Abstract

Background and objectives

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unknown etiology. Genetic and environmental factors play important roles in the pathogenesis of SLE. The primary objective of this study was to investigate the possible association of eNOS gene

mai mult
International Journal of Rheumatic Diseases
31 Decembrie 2014 05:22

Abstract

Dendritic cells (DCs) are antigen presenting cells that activate T cells and determine the outcome of immune response. In addition to their important function in defense against pathogens, DCs are increasingly recognized as playing a crucial role in the regulation of immune tolerance. Plast

mai mult
International Journal of Rheumatic Diseases
31 Decembrie 2014 05:22

Abstract

Aim

C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) are often ordered together in patients with suspected infection or inflammation. However, the test results can disagree in as many as 33% of patients. Our aim was to further examine CRP/ESR disagreements and their stab

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 02:26

Abstract

Aim

Systemic sclerosis (SSc) is characterized by immune abnormalities, progressive fibrosis of the skin and internal organs, and microvascular injury and damage. Interleukin-21 receptor (IL-21R) is expressed in the epidermis from patients with SSc. However, information describing the role of

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 03:16
26 Decembrie 2014 04:21

Abstract

While fertility is preserved in females with systemic lupus erythematosus (SLE), it is well established that pregnancy in these patients is associated with adverse maternal and fetal outcomes, including pregnancy loss, pre-eclampsia, preterm delivery and intrauterine growth retardation, as

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 04:37
26 Decembrie 2014 04:41
26 Decembrie 2014 05:21

Abstract

Aim

Human leukocyte antigen (HLA)-DRB1 allele polymorphisms have been reported to be associated with systemic lupus erythematosus (SLE) susceptibility, but the results of these previous studies have been inconsistent. The purpose of the present study was to systematically summarize and explo

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 05:59

Abstract

Aim

Rheumatoid arthritis is a chronic inflammatory autoimmune disorder with multi-factorial factors influencing disease alleviation in synovial joints. The aim of this study was to investigate the anti-arthritic efficacy of trikatu, a herbal compound, on biochemical and immunological complic

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 07:02

Abstract

Background

The aim of this study is to investigate the effects of the extended 30-month follow-up of an original trial (NCT00600197) which has been published in the Clinical Journal of Pain.

Methods

Seventy-four percent (146/197) of the participants who had taken part in the original study, i

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 07:19

Abstract

Objective

To study the factors associated with fetal loss in Chinese women with systemic lupus erythematosus (SLE) in a large cohort of SLE patients in the CSTAR (Chinese SLE Treatment and Research Group) registry.

Methods

We compared the clinical characteristics and auto-antibody profiles be

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 07:32

Abstract

The presence of the lupus erythematosus (LE) phenomenon has been generally conceptualized as an in vitro occurrence where numerous damaged cells are present and substantial nucleo-phagocytosis has occurred. In systemic lupus erythematosus (SLE), the positive LE cell phenomenon has been show

mai mult
International Journal of Rheumatic Diseases
26 Decembrie 2014 07:43

Abstract

A 55-year-old woman with newly diagnosed Takayasu arteritis was followed for 7 years, during which time she underwent bare metal stenting, drug eluting stenting and coronary bypass grafting for critical coronary and renal artery stenoses. Interventions were initially successful but resteno

mai mult
International Journal of Rheumatic Diseases
23 Decembrie 2014 09:21

Abstract

Aim

Hepatitis C virus (HCV) is sialotropic. The pathogenesis of sicca manifestations in patients with chronic HCV infection is not fully understood. We aimed to detect changes in magnetic resonance sialography (MRS) of HCV patients with and without vasculitis.

Method

We studied 32 HCV patient

mai mult
International Journal of Rheumatic Diseases
19 Decembrie 2014 06:16

Abstract

In 1983, Graham Hughes first described the concept of antiphospholipid syndrome (APS). In 1984, we described the enzyme-linked immunosorbent assay (ELISA) system which directly detected circulating aCL in patients with systemic lupus erythematosus (SLE) who revealed biological false positiv

mai mult
International Journal of Rheumatic Diseases
19 Decembrie 2014 06:46

Abstract

Aim

To describe the clinical manifestations, disease activity and organ damage in Korean patients with systemic lupus erythematosus (SLE).

Method

American College of Rheumatology (ACR) criteria, SLE Disease Activity Index (SLEDAI), and Systemic Lupus International Collaborating Clinics/ACR da

mai mult
International Journal of Rheumatic Diseases
19 Decembrie 2014 09:53

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by periods of flares and remission, resulting in organ damage over time caused by persistent disease activity and treatment-related complications. Conventional therapies are not ideal in terms of efficacy and

mai mult
International Journal of Rheumatic Diseases
19 Decembrie 2014 10:18

Abstract

Vitamin D is a steroid hormone that has well-established roles in calcium and bone metabolism. Vitamin D has more recently become recognized for its role in the immune response and its potential immunomodulatory effects in autoimmune diseases, including systemic lupus erythematosus (SLE). T

mai mult
International Journal of Rheumatic Diseases
19 Decembrie 2014 11:05

Abstract

Recent advances in systemic lupus erythematosus (SLE) genetics in Asian populations have been achieved by genome-wide association studies (GWASs) and following replication studies, which expanded the genetic information about shared or population-specific risk genes between ethnic groups. M

mai mult
International Journal of Rheumatic Diseases
20 Decembrie 2014 06:18

Abstract

Aim

To detect subclinical peripheral arthritis and disease activity in axial seronegative spondyloarthritis (SpA) patients using bone scintigraphy.

Methods

Seronegative SpA patients with an established diagnosis and no clinically evident arthritis at the time of the study were included. After

mai mult
International Journal of Rheumatic Diseases
20 Decembrie 2014 06:56

Abstract

Aim

This study aimed to determine synovial fluid and serum biomarkers which could accord with radiological and ultrasonographic findings in knee osteoarthritis.

Methods

Thirty-four patients with knee osteoarthritis were detected with joint effusion by clinical examination. Both knee joints we

mai mult
International Journal of Rheumatic Diseases
20 Decembrie 2014 08:08

Abstract

Aim

We describe the clinical profile of elderly with primary antiphospholipid syndrome (APS).

Methods

Charts of seven elderly patients diagnosed with APS between 1996 and 2012 were retrospectively assessed.

Results

The mean age at diagnosis was 77 ? 6 years (67??84 years). Two patients h

mai mult
International Journal of Rheumatic Diseases
20 Decembrie 2014 08:11

Abstract

Aim

To investigate the effects of Tubastatin A, a selective histone deacetylase-6 inhibitor, on synovial inflammation and joint destruction in a collagen antibody-induced arthritis (CAIA) mouse model.

Methods

Collagen antibody-induced arthritis mice were given daily intraperitoneal injections

mai mult
International Journal of Rheumatic Diseases
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