Home Jurnale medicale Journal of Clinical Oncology Current Issue
Jurnale medicale
Journal of Clinical Oncology Current Issue
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Jurnale medicale Journal of Clinical Oncology Current Issue

6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

To determine the cumulative incidence of and risk factors for psychiatric morbidity and establish the impact on survival among surgically treated patients with esophageal cancer.

Patients and Methods

A nationwide Swedish cohort of 1,615 patients who underwent surgery for esophageal cancer b

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

The CLEOPATRA (Clinical Evaluation of Trastuzumab and Pertuzumab) study demonstrated superior progression-free survival (PFS) and overall survival when pertuzumab was added to trastuzumab and docetaxel. Paclitaxel given once per week is effective and less toxic than docetaxel. We performed a

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

Linifanib, a potent, selective inhibitor of vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors, has single-agent activity in non–small-cell lung cancer (NSCLC). We evaluated linifanib with carboplatin and paclitaxel as first-line therapy of advanced

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

Knowledge of the contribution of high-penetrance susceptibility to familial colorectal cancer (CRC) is relevant to the counseling, treatment, and surveillance of CRC patients and families.

Patients and Methods

To quantify the impact of germline mutation to familial CRC, we sequenced the mis

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
Purpose

The objective of this study was to describe the diagnostic yield and complication rate of bronchoalveolar lavage (BAL) and lung biopsy in the evaluation of pulmonary lesions in patients with cancer and recipients of hematopoietic stem-cell transplantation (HSCT).

Methods

We conducted a syst

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
Purpose

Male pattern baldness and prostate cancer appear to share common pathophysiologic mechanisms. However, results from previous studies that assess their relationship have been inconsistent. Therefore, we investigated the association of male pattern baldness at age 45 years with risks of overal

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
Purpose

To compare age-dependent changes in health status among childhood cancer survivors and a sibling cohort.

Methods

Adult survivors of childhood cancer and siblings, all participants of the Childhood Cancer Survivor Study, completed three surveys assessing health status. At each of three time

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
Purpose

Histiocytoses are rare disorders with heterogeneous prognosis. BRAFV600E mutations have been observed in half of patients with Langerhans cell histiocytosis (LCH) and in 50% to 100% of patients with Erdheim-Chester disease (ECD) patients. We recently reported short-term efficacy of a BRAF in

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
Purpose

To validate a prognostic score predicting major complications in patients with solid tumors and seemingly stable episodes of febrile neutropenia (FN). The definition of clinical stability implies the absence of organ dysfunction, abnormalities in vital signs, and major infections.

Patients mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
Purpose

The presence of a mutated nucleophosmin-1 gene (NPM1mut) in acute myeloid leukemia (AML) is associated with a favorable prognosis. To assess the predictive value with regard to allogeneic stem-cell transplantation (SCT), we compared the clinical course of patients with NPM1mut AML eligible f

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

To create clinically useful models that incorporate readily available demographic and cancer treatment characteristics to predict individual risk of heart failure among 5-year survivors of childhood cancer.

Patients and Methods

Survivors in the Childhood Cancer Survivor Study (CCSS) free of

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
6 Februarie 2015 23:00
6 Februarie 2015 23:00
6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

To assess the risks of second malignancy and early menopause in a large cohort of patients with gestational trophoblastic tumor who were treated with chemotherapy.

Patients and Methods

A survey of patients treated at Charing Cross Hospital between 1958 and 2000 was performed in 2006 to asse

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
6 Februarie 2015 23:00
6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

To estimate the prevalence of and risk factors for growth hormone deficiency (GHD), luteinizing hormone/follicle-stimulating hormone deficiencies (LH/FSHD), thyroid-stimulatin hormone deficiency (TSHD), and adrenocorticotropic hormone deficiency (ACTHD) after cranial radiotherapy (CRT) in ch

mai mult
Journal of Clinical Oncology Current Issue
6 Februarie 2015 23:00
6 Februarie 2015 23:00
6 Februarie 2015 23:00
6 Februarie 2015 23:00
Purpose

Travel distances to care have increased substantially with centralization of complex cancer procedures at high-volume centers. We hypothesize that longer travel distances are associated with higher rates of postoperative readmission and poorer outcomes.

Methods

SEER-Medicare patients with b

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Journal of Clinical Oncology Current Issue
29 Ianuarie 2015 23:00
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