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Jurnale medicale
Journal of Gastroenterology and Hepatology
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Jurnale medicale Journal of Gastroenterology and Hepatology

30 Ianuarie 2015 09:25

Abstract

Background and Aim

To evaluate the role of antiviral therapy with nucleoside analogues (NAs) in sorafenib treated patients with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC).

Methods

A retrospective cohort study was done in 151 HBV-related HCC patients treated with sora

mai mult
Journal of Gastroenterology and Hepatology
5 Ianuarie 2015 08:40

Abstract

Background and Aim

Non-erosive reflux disease (NERD) and functional dyspepsia (FD) share some common features, and the appropriateness of managing these diseases independently has been questioned. A post hoc subgroup analysis of the LEGEND study was performed to compare demographics and trea

mai mult
Journal of Gastroenterology and Hepatology
5 Ianuarie 2015 08:40

Background and Aims

Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. In this study, we investigated the role of miR-146b in the TLR-4 signaling pathway and high-fat diet (HFD)-induced NASH in vivo and in vitro.

Methods

The effect of miR-146b on the

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 09:58

Abstract

Background and Aims

Endoscopic submucosal dissection (ESD) is now commonly performed as a treatment for colorectal tumors. However, little is known about the relationship between submucosal fibrosis and the outcome of the colonic ESD procedure. The aims of this study were to investigate the

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 09:58

Abstract

Background

Anatomic left hepatic trisectionectomy (ALHT)is a complex hepatic resection, and its outcomes inhepatocellular carcinoma (HCC) still remain unclear.This paper focuses on the assessment of the safety and long-term effects of ALHT on intermediate and advanced hepatocellular carcinom

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 09:58

Abstract

Background

One single-nucleotide polymorphisms (SNP) rs738409 in the patatin-like phospholipase domain-containing 3 gene (PNPLA3) has been implicated in susceptibility to non-alcoholic fatty liver disease (NAFLD) across different populations. One meta-analysis confirmed this association, but

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 09:59

Abstract

Background/Aims

Interleukin-28B (IL28B) and patatin-like phospholipase domain containing 3 (PNPLA3) gene polymorphisms are associated with hepatitis C virus (HCV) clearance and fatty liver, respectively. We aimed to test if their polymorphisms are associated with virologic responses in Chine

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 10:21

Abstract

Background

Excretion of the patency capsule (PC) within a certain timeframe may be used to demonstrate luminal patency prior to capsule endoscopy (CE). We aimed to determine how often further radiological imaging is needed to confirm luminal patency after PC, assess radiologists?? ability t

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 10:22

Abstract

Background and aim

Comparisons of intraductal ultrasonography (IDUS) findings between primary sclerosing cholangitis (PSC) and IgG4-related sclerosing cholangitis (IgG4-SC) have not been elucidated. We aimed to clarify the differences in transpapillary IDUS findings between PSC and IgG4-SC.

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 16:39

Abstract

Ipilimumab has been shown to improve overall survival in patients with advanced melanoma. Ipilimumab acts through immune-modulation, and is recognised to cause potentially severe immune-related adverse events (irAEs) including dermatitis, colitis, thyroiditis, hypophysitis and hepatitis. Th

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 16:39

Abstract

Background and aim

Clarithromycin-based triple therapy (TT) is the first line treatment for H. pylori infection in Singapore. There is awareness that TT may no longer be effective due to increased clarithromycin resistance rates. Sequential therapy (ST) and concomitant therapy (CT) are alter

mai mult
Journal of Gastroenterology and Hepatology
16 Ianuarie 2015 16:39

Abstract

Background and Aim

Recent studies show that adipose tissue-derived mesenchymal stem cells have potential clinical applications. However, the mechanism has not been fully elucidated yet. Here, we investigated the effect of basic fibroblast growth factor-treated adipose tissue-derived mesenchy

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:00

Abstract

Background and aim

Sorafenib is now considered as a standard treatment for advanced hepatocellular carcinoma (HCC). We evaluated the effect of hepatitis B virus (HBV) DNA titers on prognosis in HCC patients treated with sorafenib.

Methods

From 2008 to 2012, 78 HBV-related HCC patients who rec

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:07

Abstract

Background and Aim

The prevalence of gastroesophageal reflux disease (GERD) in adults is increasing in Japan as well as worldwide likely due to increasing obesity and the decreasing rate of Helicobacter pylori infection. However, data regarding the prevalence of GERD in children and adolesce

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:08

Abstract

Biliary atresia (BA) is characterized by periductular inflammation and fibrosis and is associated with the progressive obliteration of the bile ducts. The induction and maintenance of systemic and local inflammatory responses plays a pivotal role in this process. Interleukin-8 (IL-8) is an

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:08

Abstract

Background

The hepatitis C virus (HCV) may promote pancreatic ?-cell apoptosis-like cell death through a caspase 3-dependent pathway, initiating the onset of Type 2 diabetes; however, the risk factors for development of Type 2 diabetes and other abnormal glycometabolic factors in HCV patien

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:08

Abstract

Background

Interferon (IFN) ? plays an important role in innate immunity to protect against hepatitis C viral (HCV) infection. Single nucleotide polymorphisms (SNPs) near IL28B (IFN?3) are strongly associated with treatment response to IFN? therapy in chronic hepatitis C (CHC) patients. R

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:08

Abstract

Background & Aims

There is limited information about the interplay between multiple risk factors contributing to the risk of advanced neoplasia. We determined the actual risk for advanced neoplasia in relation to lapsed time between colonoscopies in people enrolled in a structured surveillan

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:08

Abstract

Background and Aim

Aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) is a transcriptional regulator and member of the basic helix-loop-helix/Per-ARNT-SIM (bHLH/PAS) superfamily. Recently, evidence of that ARNT is involved in carcinogenesis and cancer progression has emerged. The aim o

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:09

Abstract

Background and Aim

Small intestinal bacterial overgrowth which has recently been diagnosed with the glucose breath test is characterized by excessive colonic bacteria in the small bowel, and results in gastrointestinal symptoms that mimic symptoms of inflammatory bowel disease. This study ai

mai mult
Journal of Gastroenterology and Hepatology
22 Ianuarie 2015 10:09

Abstract

Barrett's esophagus (BE), a common condition, is the only known precursor to esophageal adenocarcinoma (EAC). There is uncertainty about the best way to manage BE, since most people with BE never develop EAC and most patients diagnosed with EAC have no preceding diagnosis of BE. Moreover, t

mai mult
Journal of Gastroenterology and Hepatology
26 Ianuarie 2015 10:06

Abstract

Background and Aim

Major depressive disorder (MDD) is an important public-health problem, and it is often comorbid with many chronic diseases. The purpose of this study was to identify the clinical features of non-alcoholic fatty liver disease (NAFLD) patients comorbid with MDD, and to inves

mai mult
Journal of Gastroenterology and Hepatology
30 Decembrie 2014 10:07

Abstract

Background & Aims

It was commonly accepted that chemotherapeutic cytotoxicity was the main cause for hepatic failure in Hepatocellular carcinoma (HCC) patients after repeated transarterial chemoembolization (TACE). However, the effect of embolization-induced hypoxia on liver cirrhosis has ra

mai mult
Journal of Gastroenterology and Hepatology
23 Decembrie 2014 05:58

Abstract

Background and aim

The prevalence of Helicobacter pylori-negative and non-steroidal anti-inflammatory drug (NSAID)-negative peptic ulcers, commonly known as idiopathic peptic ulcers (IPUs), has been reported to be very low (0.9??2.6%) in Japan based on data from the 1990s. However, recent t

mai mult
Journal of Gastroenterology and Hepatology
23 Decembrie 2014 06:08
23 Decembrie 2014 06:09

Abstract

Backgroud& aims

Previous studies have indicated that lamivudine-induced hepatitis B e antigen (HBeAg) seroconversion may not be durable in the Asian population. We investigated the useful predictors of post-treatment hepatitis B virus (HBV) relapse in patients with nucleos(t)ide analogue (NA

mai mult
Journal of Gastroenterology and Hepatology
23 Decembrie 2014 06:09

Abstract

Background and Aim

Impaired splanchnic hemodynamics are well-documented phenomena in cirrhosis. However, comprehensive hemodynamic features from the superior mesenteric artery (SMA) to the superior mesenteric vein (SMV) via intestinal capillaries have not been studied. The aim was to examine

mai mult
Journal of Gastroenterology and Hepatology
23 Decembrie 2014 06:55

Abstract

Background and Aim

Rejection of liver grafts is a difficult issue that has not been resolved. Preoperative replacement of liver cells in the graft with cells from the intended recipient may attenuate rejection. We investigated whether preoperative transplantation of recipient BMCs to the don

mai mult
Journal of Gastroenterology and Hepatology
23 Decembrie 2014 12:27
23 Decembrie 2014 12:27
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