Home Jurnale medicale Journal of the American College of Cardiology Current Issue
Jurnale medicale
Journal of the American College of Cardiology&n...
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Jurnale medicale Journal of the American College of Cardiology Current Issue

10 Februarie 2015
We thank Drs. Capodanno and Lip for their interest in and valuable comments on our recent review (1) on triple therapy for atrial fibrillation (AF) and percutaneous coronary intervention (PCI). mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
A structurally normal mitral valve when abnormally tethered in a dilated ventricle will startto leak once the available closing force becomes insufficient to achieve effective systolic leaflet coaptation (1). Conversely, diastolic tethering may restrict leaflet mobility and thus limit complete openi mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
We thank Dr. Madias for his interest in our analysis (1) and his comments regarding QRS amplitude as well asthe role of left ventricular (LV) lead positioning in terms of response to cardiac resynchronization therapy (CRT). QRS amplitude could be important but is not available in the National Cardio mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Background
Restrictive mitral valve annuloplasty (RMA) for secondary mitral regurgitation might cause functional mitral stenosis, yet its clinical impact and underlying pathophysiological mechanisms remain debated.
Objectives
The purpose of our study was to assess the hemodynamic and clinical impact of
mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
We previously developed a tissue-engineered vascular graft (TEVG), created by seeding a biodegradable scaffold with autologous bone marrowderived mononuclear cells, specifically designed for use in congenital heart surgery. We demonstrated in a clinical trial that this approach is safe and effective mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
The paper by Urena etal. (1) in this issue of the Journal deserves our most careful attention. Now that transcatheter aortic valve implantation (TAVI) has reached relative maturity in terms of equipment, technical strategy, and screening refinement, and given that eligibility of patients at intermed mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
It was graduation day for 1 of the biggest and most prestigious pediatric residency programs in the country. Families came from every state to see their children graduate. Omars family could not join him from overseas today, as they were not able to get the visa in time. The big news today was that mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Background
Little evidence exists of the burden and predictors of cardiac death after transcatheter aortic valve replacement (TAVR).
Objectives
The purpose of this study was to assess the incidence and predictors of cardiac death from advanced heartfailure (HF) and sudden cardiac death (SCD) in a large
mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
The overwhelming majority of sports-related sudden deaths occur among those older than 35 years of age. Because increasing numbers of older people are participating in organized endurance and competitive sporting events, the incidence of sports-related sudden death in older adults is expected to ris mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
The spectrum and epidemiology of aortic valve stenosis (AVS) have changed drastically since the 1968 seminal report from Ross and Braunwald (1). The prevalence of AVS has been steadily increasing with age in the general population (2). Compared to earlier generations, patients undergoing surgical ao mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
For more than a decade, dual antiplatelet therapy with aspirin and clopidogrel has been thestandard of care for patients presenting with acute coronary syndrome (ACS) (1). However, the therapeutic landscape has changed dramatically with the introduction of prasugrel and ticagrelor, which improve cli mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Background
Systemic arterial load impacts the symptomatic status and outcome of patients with calcific degenerative aortic stenosis (AS). However, assessing vascular properties is challenging because the arterial trees behavior could be influenced by the valvular obstruction.
Objectives
This study soug
mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
A 35-year-old Caucasian female with a history of systemic vasculitis and suspicion of polyarteritis nodosa was referred for evaluation of recurrent chest pain. The echocardiogram showed a normal left ventricular ejection fraction and an ambiguous 30-mm-wide hypoechoic structure lateral to the right mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Although it is well known that regular exercise and physical activity (PA) have health benefits, there is still an unanswered question: Is it possible to have too much of a good thing? In particular, is high-intensity PA, such as running, a healthful activity? The dose-response relationship between mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Zusterzeel etal. (1) reported in the September 2, 2014, issue of the Journal on the predictive merits of QRS morphology and QRS duration (QRSd) following implementation of cardiac resynchronization therapy (CRT), analyzing 31,892 patients from the National Cardiovascular Data Registry (NCDR) Implant mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Background
People who are physically active have at least a 30% lower risk of death during follow-up compared with those who are inactive. However, the ideal dose of exercise for improving longevity is uncertain.
Objectives
The aim of this study was to investigate the association between jogging and lo
mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
More than a decade ago, on February 5, 2002, precisely, a document was published that was the result of a project undertaken by the American Board of Internal Medicine Foundation, the American College of PhysiciansAmerican Society of Internal Medicine Foundation, and the European Federation of Inter mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
10 Februarie 2015
Background
Based on results of the PLATO (Platelet Inhibition and Patient Outcomes) trial comparing ticagrelor with clopidogrel therapy, the U.S. Food and Drug Administration approved ticagrelor in 2011 for reducing thrombotic cardiovascular events in patients with acute coronary syndrome (ACS) with
mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Complete heart block developed in a 70-year-old woman for which a pacer was inserted at an outside institution. Two months later, increasing dyspnea prompted admission with severe jugular venous distention and hepatic enlargement.Transthoracic echocardiography demonstrated massive soft-tissue infilt mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
In healthy volunteers, 300 mg clopidogrel administered crushed via a nasogastric tube results in faster and greater bioavailability of the drug compared with whole tablets administered orally (1). Recently, Crean et al. (2) reported that ticagrelor tablets could be easily crushed and prepared for or mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
A 29-year-old woman with no history of heart disease presented with symptoms of palpitations and chest congestion after activity for 1 month. On physical examination, she had a precordium continuous murmur. Findings on electrocardiography were normal. Chest radiography in the posteroanterior view re mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
We read with interest the review article from Dewilde et al. (1) who nicely summarize the available evidence on triple antithrombotic therapy in patients with atrial fibrillation (AF) undergoing coronary stenting. The authors conclude that the combination of vitamin K antagonists (VKA) and clopidogr mai mult
Journal of the American College of Cardiology Current Issue
10 Februarie 2015
Hyponatremia frequently poses a therapeutic challenge in acute decompensated heart failure (ADHF). Treating physicians should differentiate between depletional versus dilutional hyponatremia. The former is caused by diuretic agents, which enhance sodium excretion, often with concomitant potassium/ma mai mult
Journal of the American College of Cardiology Current Issue
3 Februarie 2015
We reported that during the popular endurance racestaking place in Tel Aviv during the last 6 years (involving almost 140,000 runners), there were only 2 serious cardiac events, neither of which were life-threatening. In contrast, there were 21 serious cases of heat stroke, including 2 that were fat mai mult
Journal of the American College of Cardiology Current Issue
3 Februarie 2015
The current understanding of heart failure (HF) does not fully explain the spectrum of HF symptoms. Most HF hospitalizations are related to sodium (Na+) and fluid retention resulting from neurohumoral up-regulation. Recent insights suggest that Na+ is not distributed in the body solely as a free cat mai mult
Journal of the American College of Cardiology Current Issue
3 Februarie 2015
The data presented by Yankelson etal. (1) that define the incidence of heat stroke in long distance races, and the relationship of this condition to the epidemiology of exercise-related illness and sudden death, clearly increases our understanding of the risks that athletes face performing in such e mai mult
Journal of the American College of Cardiology Current Issue
3 Februarie 2015
Variations in clinical expression of genetically based disorders are common, especially for syndromes characterized by complex physiological pathways. Although not unique to the inherited long QT syndromes (LQTS), patterns of complex interactions are particularly striking in families in which multip mai mult
Journal of the American College of Cardiology Current Issue
3 Februarie 2015
We thank Dr. Rasekh and colleagues for their interest in our multicenter study of transcatheter left atrial appendage (LAA) closure with the Lariat suture delivery device (SentreHeart, Redwood City, California) (1). They cite concerns about the participating centers, operator training, and inclusion mai mult
Journal of the American College of Cardiology Current Issue
3 Februarie 2015
Background
A puzzling feature of the long QT syndrome (LQTS) is that family members carrying the same mutation often have divergent symptoms and clinical outcomes.
Objectives
This study tested the hypothesis that vagal and sympathetic control, as assessed by spectral analysis of spontaneous beat-to-bea
mai mult
Journal of the American College of Cardiology Current Issue
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