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Jurnale medicale The Lancet Infectious Diseases

20 Octombrie 2014 23:01
In the face of diminishing therapeutic options for the treatment of infections caused by multidrug-resistant, Gram-negative bacteria, clinicians are increasingly using colistin and polymyxin B. These antibiotics became available clinically in the 1950s, when understanding of antimicrobial pharmacolo mai mult
The Lancet Infectious Diseases
5 Noiembrie 2014 00:01
This summer, The London School of Hygiene & Tropical Medicine (LSHTM) commemorated the 100th anniversary of the start of World War 1 with an exhibition and a series of lectures focusing on the work of tropical medicine and public health professionals during conflicts since The Great War, including t mai mult
The Lancet Infectious Diseases
11 Noiembrie 2014 05:41
Despite control efforts, the burden of health-care-associated infections in Europe is high and leads to around 37??000 deaths each year. We did a systematic review to identify crucial elements for the organisation of effective infection-prevention programmes in hospitals and key components for impl mai mult
The Lancet Infectious Diseases
14 Noiembrie 2014 00:01
A 49-year-old man with a history of hypertension and type 2 diabetes mellitus was referred for an internal medicine consultation because of worsening heartburn for the past 3 months. The patient regularly ate pickled anchovies (raw anchovies in vinegar sauce). His overall health was good, and findin mai mult
The Lancet Infectious Diseases
19 Noiembrie 2014 00:01
In their analysis of Ebola transmission,1 Joseph Lewnard and colleagues emphasise the need for an ??acceleration of case ascertainment?, which so far has been a major challenge. Most patients with Ebola in west Africa remain undiagnosed in their communities,2 and the average delay from symptom on mai mult
The Lancet Infectious Diseases
19 Noiembrie 2014 00:01
Semen is one of the body fluids from which Ebola virus disease can be contracted, presumably by delivery of the infectious virus to a mucosal surface. WHO notes that Ebola viruses can be transmitted via the semen of a man who is convalescing, for up to 7 weeks after recovery from an Ebola virus infe mai mult
The Lancet Infectious Diseases
19 Noiembrie 2014 00:01
For more than two decades, CD4 cell count measurements have been central to understanding HIV disease progression, making important clinical decisions, and monitoring the response to antiretroviral therapy (ART). In well resourced settings, the monitoring of patients on ART has been supported by rou mai mult
The Lancet Infectious Diseases
21 Noiembrie 2014 02:59
We present a case of fulminant Pasteurella multocida sepsis in a 66-year-old man who had undergone a renal transplant. Our patient lived with two dogs and a cat with which he was very close. We propose that his bacteraemia might have resulted from direct inoculation of P multocida via his cat lickin mai mult
The Lancet Infectious Diseases
28 Noiembrie 2014 00:01
Although several antivirals have shown efficacy against Ebola virus infection in vitro or in animal models, none of them have been yet assessed in human beings with Ebola virus disease. mai mult
The Lancet Infectious Diseases
22 Decembrie 2014 00:01
??B venatorum? infection should be included in the differential diagnosis of patients with a tick-exposure history in areas where this pathogen has previously been identified in ticks or people. mai mult
The Lancet Infectious Diseases
22 Decembrie 2014 00:01
Ceftaroline fosamil 600 mg given every 12 h was superior to ceftriaxone 2 g given every 24 h for the treatment of Asian patients with PORT III??IV community-acquired pneumonia. These data suggest that ceftaroline fosamil should be regarded as an alternative to ceftriaxone in empirical treatment reg mai mult
The Lancet Infectious Diseases
22 Decembrie 2014 00:01
Community-acquired pneumonia is the leading cause of hospital admissions for infectious disease in Europe, and a major cause of morbidity and mortality. According to the results of Global Burden of Disease study,1 in the WHO European region, community-acquired pneumonia accounted for 230??000 (2?3 mai mult
The Lancet Infectious Diseases
22 Decembrie 2014 00:01
In The Lancet Infectious Diseases, Jia-Fu Jiang and colleagues report 48 cases of ??Babesia venatorum? infection in a northeastern forested province of China between 2011 and 2014.1 This case series is the largest ever reported for ??B venatorum? and the first description of a ??B venatorum? mai mult
The Lancet Infectious Diseases
23 Decembrie 2014 00:01
One in ten children with molluscum contagiosum is likely to have a substantial effect on their quality of life and therefore treatment should be considered for some children, especially those with many lesions or who have been identified as having a severe effect on quality of life. Patients with mo mai mult
The Lancet Infectious Diseases
23 Decembrie 2014 00:01
Molluscum contagiosum, a common viral cutaneous infection in children, is caused by a poxvirus of the molluscipox genus. The infection accounts for roughly 1% of all diagnosed skin disorders.1 Despite its common occurrence, little has been published on the natural history of molluscum contagiosum.2 mai mult
The Lancet Infectious Diseases
7 Ianuarie 2015 00:01
The model allows assessment of intervention options and the understanding of their role in the decrease in incidence reported since Sept 7, 2014. High-quality data (eg, to estimate household secondary attack rate, contact patterns within hospitals, and effects of ongoing interventions) are needed to mai mult
The Lancet Infectious Diseases
7 Ianuarie 2015 00:01
What initially was perceived to be a self-limited outbreak of Ebola virus disease in a forested area of Guinea has become an unprecedented epidemic of international concern that continues to spread unabated in parts of west Africa.1,2 A lack of public health infrastructure together with delays in vi mai mult
The Lancet Infectious Diseases
8 Ianuarie 2015 00:01
Use of different (alternating) limbs for sequential doses of routine infant vaccines does not reduce, and might enhance, immunogenicity. The underlying mechanism for this finding warrants further research. mai mult
The Lancet Infectious Diseases
8 Ianuarie 2015 00:01
Despite the remarkable successes of immunisation programmes in reducing the global burden of infectious diseases, substantial gaps remain in our basic understanding of vaccine science. Some of these gaps are pathogen-related, such as the identification of protective epitopes, and others are host-rel mai mult
The Lancet Infectious Diseases
9 Ianuarie 2015 00:01
Our findings show a moderate increased risk of HIV acquisition for all women using depot medroxyprogesterone acetate, with a smaller increase in risk for women in the general population. Whether the risks of HIV observed in our study would merit complete withdrawal of depot medroxyprogesterone aceta mai mult
The Lancet Infectious Diseases
9 Ianuarie 2015 00:01
The question of whether hormonal contraception, particularly depot medroxyprogesterone acetate, increases a woman's risk of acquiring HIV has been debated since an association was first noted in 1991.1 Subsequent data from observational studies, secondary analyses of trials, and systematic reviews2 mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
A new rabies control programme in India aims to tackle the serious but under-recognised public-health burden caused by this disease. Sanjeet Bagcchi reports. mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
At present, there is a clarion call for action on climate change across the global health landscape.1,2 At the recent WHO-sponsored conference on health and climate (held in Geneva, Switzerland, on Aug 27??29, 2014) and the UN Climate Summit (New York, USA, on Sept 23, 2014), participants were enco mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
Amidst concerns of Ebola virus disease becoming a pandemic, the global medical community has mounted a crucial response. As the director of the US Centers for Disease Control and Prevention has said, ??we have to work now so this is not the world's next AIDS.?1 Although different from HIV/AIDS, w mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
In clinical trial settings the standard 6-month treatment regimen for drug-sensitive pulmonary tuberculosis can achieve relapse-free cure in more than 95% of people. However, poor adherence might increase the risk of relapse and lead to drug resistance. Shortening the duration of treatment has becom mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
The 2014 International Sepsis Forum was held in Paris (Dec 2??5). The conference covered topics from the basic molecular biology of sepsis to clinical trials. Raffaella Bosurgi reports. mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
As of the Dec 30, 2014, 32 people in 11 states have fallen ill with the outbreak strain of Listeria monocytogenes. Since the initial illness onset dates around Oct 17, 2014, 31 people have been admitted to hospital. Ten cases were associated with pregnancy, of which one led to loss of the fetus. Six mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
Ebola needs to be contained. Despite this basic epidemiological truth, we have difficulty understanding the intelligence, money, and institutional efforts dedicated to this disease. mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
A study provides evidence for an interaction between respiratory syncitial virus (RSV) and Streptococcus pneumonia infections. An analysis of data collected between 1992 and 2009 on hospital admissions for RSV and for pneumococcal pneumonia among US children younger than 2 years shows that the two d mai mult
The Lancet Infectious Diseases
31 Ianuarie 2015 22:00
Almost 20??000 cases of Ebola virus disease have been reported in west Africa.1 Estimates of the reproductive ratio of the outbreak2??5 suggest that about half of infectious contacts need to be prevented to control the epidemic. The international response in the affected regions has focused mainly mai mult
The Lancet Infectious Diseases
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